Israel's defence and intelligence establishment fear that if the Saudis obtain an enrichment capability, it will set off a regional cascade, with Egypt, Türkiye and the UAE likely to insist on the same, and Iran's nuclear program effectively normalised. Israel's status as the region's sole nuclear power, which underwrites its national survival, will be undermined.
Netanyahu's current governing coalition will be unable to support such a deal. But if he is able to reconfigure his governing coalition, and willing to risk his prime ministership, there is probably a majority in Israel's Knesset that could support such a deal.
The domestic politics for each country is difficult. But if respective leaders can prevail, the potential is great.
For the United States, it would help de-risk the region, counter China's inroads in the Gulf, and be a substantial diplomatic achievement for Biden in the lead-up to the 2024 elections.
For Israel, a formal end to the Arab–Israeli conflict would cement its place in the region and serve as a security asset, just as the peace treaties with Egypt and Jordan have done. For Netanyahu, it would fulfil his historic sense of mission to safeguard Israel for the future.
For Saudi Arabia, a US security guarantee will safeguard its future, while normalisation with Israel will provide a valuable strategic partner for managing the region and a source of economic dynamism. And it would burnish Crown Prince Mohammed bin Salman's modernising and reformist credentials.
Deep structural changes have made this diplomacy possible.
China is now a significant actor in the Middle East, introducing a new element of US–China strategic competition, and giving the region geopolitical choices and hence leverage.
The Arab–Israeli conflict has lost its potency among the Arab street, giving political leaders more scope for diplomatic flexibility.
Iran's ambition for regional dominance has brought into existence new balancing coalitions.
And the reality of US strategic disengagement from the region is fostering a new sense of strategic maturity, compelling the region to take more responsibility for its own security.
A “new Middle East” has often been proclaimed. This time it might actually eventuate.